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عمومی::
اختلال شناختی
HUMANIZED ANTIBODY FOR TREATING OR PREVENTING COGNITIVE DISORDERS, PROCESS FOR PRODUCING THE SAME, AND AGENT FOR TREATING OR PREVENTING COGNITIVE DISORDERS USING THE SAME
[0003] The present disclosure relates to a humanized antibody for use in the therapeutic or prophylactic treatment of cognitive disorders, a process of producing the humanized antibody, a therapeutic or prophylactic agent for cognitive disorders using the antibody, and methods for treatment or prevention of cognitive disorders using the therapeutic agents disclosed herein.
More specifically, the present disclosure relates to a novel humanized anti-phosphorylated tau antibody having excellent effect of improving cognitive function, a process of producing the humanized antibody, a therapeutic or prophylactic agent for cognitive disorders containing the humanized antibody, and methods for treatment or prevention of cognitive disorders using the humanized anti-phosphorylated tau antibody.
[0004] A cognitive disorder, or dementia, is a condition where developed intelligence deteriorates due to some acquired cause, resulting in a hindrance to social adaptation.
Cognitive disorders are classified as neurodegenerative diseases, vascular cognitive diseases, prion diseases, infectious diseases, metabolic/endocrine diseases, trauma and cerebral surgical diseases, and toxic diseases (see Toshifumi Kishimoto & Shigeki Takahashi (Edit.)
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